META-TTE - Transparent reporting of meta-analyses of time-to-event outcomes based on aggregate data from randomised trials of interventions

Literature reviews

Poor reporting of time-to-event analyses in trial publications, including outcome definitions, general and time-to-event specific methods and study characteristics can hinder the development of time-to-event meta-analyses.

To address these limitations and to improve the reporting of such meta-analyses, a group from Germany is developing a reporting guideline to be used em conjunction with PRISMA, but specifically focused on time-to-event outcomes.

The group is conducting an online open survey among experts in evidence synthesis, methodologists and statisticians to identify and confirm relevant reporting items and their definition. After a first round of feedback, they will invite participants for consultatory calls, to discuss discrepancies.

The group has-registered a protocol at OSF: https://osf.io/j5bmw. They plan to publish the reporting guidelines in late 2024, as open-access documents if funding becomes available for that.

Registered: 27 April 2023

Last updated:

Contact: Nicole Skoetz and Marius Goldkuhle Email: [email protected]; [email protected]